What Is THC-P?
Delta-9-tetrahydrocannabiphoral, or THC-P, is a cannabinoid closely related to THC that was discovered in very low concentrations in the cannabis plant in late 2019.
What sets THC-P apart is its longer alkyl side chain, which is a longer string of carbon atoms compared to traditional THC. This structural difference allows THC-P to attach more firmly to receptors throughout the body. As a result, THC-P interacts with the endocannabinoid system in a similar manner to THC but with a much greater affinity for cannabinoid receptors. Studies have shown that THC-P binds to CB1 receptors 33 times more often than conventional THC, indicating that THC-P may be up to 33 times more potent than THC. Therefore, much less THC-P is required to produce the same effects compared to THC.
THC-P Effects and Potency
Due to its strong binding to cannabinoid receptors, THC-P may have effects similar to delta 9 THC but potentially more pronounced. Researchers conducted standard cannabis mouse experiments to measure the physical effects of THC-P. Mice showed reduced activity levels at lower doses and entered a trance-like state at higher doses. In addition, higher doses of THC-P appeared to be effective in relieving pain, while other researches showed promise in relieving nausea and insomnia.
It is worth noting that even trace amounts of THC-P in existing cannabis strains may have been responsible for some of the known healing abilities of cannabis. The discovery of this extremely potent THC-like phytocannabinoid suggests that there may be pharmacological effects in cannabis that cannot be fully attributed to delta 9 THC alone. However, the strong binding affinity of THC-P also amplifies the typical unwanted side effects of THC, such as dry mouth, dry eyes, anxiety, and paranoia. It may even introduce new risks to users. Without sufficient research on human subjects, it is challenging to determine the full extent of these effects. Further studies are needed to fully understand the benefits and potential risks associated with THC-P use.
Side Effects of THC-P
In terms of safety, since there is limited evidence available, it is important for THC-P users to proceed with caution. Its safety profile is likely comparable to that of THC, as their molecular makeup is similar. While there are no known long-term negative consequences of THC-P reported yet, consuming excessive amounts can lead to unpleasant side effects such as dizziness, dry mouth, or drowsiness.
In the absence of available studies, it is important for individuals to exercise caution when considering THC-P as a potential drug until more information becomes available. While THC-P shows promise in terms of its potency and potential medicinal effects, its specific benefits and side effects are still not well-established.
One aspect to consider is that THC-P is typically present in cannabis in low concentrations. This makes it difficult to determine the overall impact of THC-P on the effects of marijuana. It is theorized that THC-P could be one of the reasons why certain cannabis strains are more potent despite having similar or lower concentrations of THC. However, there is currently no clear evidence to support this concept.
Is THC-P legal?
When it comes to the legal status of THC-P, it is important to examine the regulations in different regions.
A. In Europe
THC-P is not classified as an isomer or stereoisomer of THC, and therefore it is not scheduled as a controlled substance on the EU Green List. If the THC-P raw material is derived from natural cannabis and not completely synthesized in a laboratory, it is likely to fall outside the scope of the European "New Drug Law." However, the specific regulations regarding THC-P under the NPSG law in Germany, for example, are not entirely clear.
B. In the USA
Under the Farm Bill of 2018, hemp and hemp-derived products with a THC content of 0.3% or less are legal under federal law in the United States. While THC-P is permitted by federal law, the situation becomes more complicated at the state level. Some states have implemented laws that either outlaw or heavily regulate intoxicating hemp derivatives, including THC-P. Therefore, it is important to be aware of the regulations specific to one's state.
Will THC-P show up on my drug test?
As for drug tests, since THC-P has not been extensively researched, it is difficult to determine whether it will result in a failed drug test. Generally, if a cannabinoid's name contains the letters "THC," there is a presumption that it could lead to a positive drug test. Standard drug tests typically detect the THC-COOH enzyme, which breaks down THC-based cannabinoids. Given the higher potency of THC-P compared to delta 9 THC, it is reasonable to assume that THC-P could potentially screen positive for drugs more frequently than THC. Therefore, individuals who anticipate a drug test should avoid THC-P consumption for several weeks prior to the test.
How to buy THC-P?
If you are interested in trying THC-P, it is important to note that it is still a relatively new and emerging cannabinoid. As a result, the availability of THC-P products may be limited compared to more well-known cannabinoids like THC and CBD. However, there are some THC-P products starting to emerge in the market.
When considering THC-P products, it is essential to source them from reputable and trusted suppliers. Look for products that have undergone testing for potency, purity, and contaminants to ensure that you are getting a safe and reliable product.
In conclusion, while THC-P is still an emerging cannabinoid, it holds promise in the cannabis industry. However, the availability of THC-P products may be limited, and it is crucial to approach its use with caution and start with a low dose. As with any substance, prioritizing safety, informed decision-making, and consulting with a healthcare professional when necessary are key when considering THC-P products.